Lake Andes, SD is a city located in Charles Mix County, South Dakota and has a land area of 168.54 square miles (436.52 km2). The water area for the city is 14.78 square miles or 38.28 km2. There is one unique zip code in Lake Andes, South Dakota and it is 57356. The area code(s) for Lake Andes is 605.
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